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1

Benzofuran derivatives as ETA-selective, non-peptide endothelin antagonists

JS Kaltenbronn, J Quin III, BR Reisdorph, S Klutchko, EE Reynolds, KM Welch, MA Flynn, AM Doherty

Journal:

European Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 601 KB

english, 1997

2

Renin inhibitors containing esters at the P2-position. Oral activity in a derivative of methyl aminomalonate

Repine, Joseph T., Himmelsbach, Richard J., Hodges, John C., Kaltenbronn, James S., Sircar, Ila, Skeean, Richard W., Brennan, Sean T., Hurley, Timothy R., Lunney, Elizabeth

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 2.33 MB

english, 1991

3

G-Protein Signaling Participates in the Development of Diabetic Cardiomyopathy

Harris, I. S., Treskov, I., Rowley, M. W., Heximer, S., Kaltenbronn, K., Finck, B. N., Gross, R. W., Kelly, D. P., Blumer, K. J., Muslin, A. J.

Journal:

Year:

2004

Language:

english

File:

PDF, 300 KB

english, 2004

4

Postnatal induction and localization of R7BP, a membrane-anchoring protein for regulator of G protein signaling 7 family-Gβ5 complexes in brain

D. Grabowska, M. Jayaraman, K.M. Kaltenbronn, S.L. Sandiford, Q. Wang, S. Jenkins, V.Z. Slepak, Y. Smith, K.J. Blumer

Journal:

Year:

2008

Language:

english

File:

PDF, 3.61 MB

english, 2008

5

R7BP Augments the Function of RGS7{middle dot}Gbeta5 Complexes by a Plasma Membrane-targeting Mechanism

Drenan, R. M., Doupnik, C. A., Jayaraman, M., Buchwalter, A. L., Kaltenbronn, K. M., Huettner, J. E., Linder, M. E., Blumer, K. J.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 984 KB

english, 2006

6

Modified di- and tripeptides of the C-terminal portion of oxytocin and vasopressin as possible cognition activation agents

Nicolaides, E. D., Tinney, F. J., Kaltenbronn, J. S., Repine, J. T., DeJohn, D. A., Lunney, E. A., Roark, W. H.

Journal:

Journal of Medicinal Chemistry

Year:

1986

Language:

english

File:

PDF, 1.46 MB

english, 1986

7

Renin inhibitors containing isosteric replacements of the amide bond connecting the P3 and P2 sites

Kaltenbronn, James S., Hudspeth, J. P., Lunney, E. A., Michniewicz, B. M., Nicolaides, E. D., Repine, J. T., Roark, W. H., Stier, M. A., Tinney, F. J.

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 1.06 MB

english, 1990

8

ChemInform Abstract: Modified Di- and Tripeptides of the C-Terminal Portion of Oxytocin and Vasopressin as Possible Cognition Activation Agents.

NICOLAIDES, E. D., TINNEY, F. J., KALTENBRONN, J. S., REPINE, J. T., DEJOHN, D. A., LUNNEY, E. A., ROARK, W. H., MARRIOT, J. G., DAVIS, R. E., WOIGTMAN, R. E.

Journal:

Chemischer Informationsdienst

Year:

1986

File:

PDF, 99 KB

1986

9

ChemInform Abstract: Benzofuran Derivatives as ETA-Selective, Non-Peptide Endothelin Antagonists.

J. S. KALTENBRONN, J. III QUIN, B. R. REISDORPH, S. KLUTCHKO, E. E. REYNOLDS, K. M. WELCH, M. A. FLYNN, A. M. DOHERTY

Journal:

Year:

1997

File:

PDF, 33 KB

1997

10

Synthesis and structure activity relationships of potent new angiotensin converting enzyme inhibitors containing saturated bicyclic amino acids

Blankley, C. J., Kaltenbronn, J. S., DeJohn, D. E., Werner, A., Bennett, L. R., Bobowski, G., Krolls, U., Johnson, D. R., Pearlman, W. M.

Journal:

Journal of Medicinal Chemistry

Year:

1987

Language:

english

File:

PDF, 970 KB

english, 1987

11

Design and Synthesis of Renin Inhibitors: Incorporation of Transition-State Isostere Side Chains That Span from the S1 to the S3 Binding Pockets and Examination of P3-Modified Renin Inhibitors

Shahripour, Aurash, Kaltenbronn, James S., Lunney, Elizabeth A., Steinbaugh, Bruce A., Hamby, James M., Hamilton, Harriet W., Sawyer, Tomi K., Humblet, Christine, Doherty, Annette M.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 2.43 MB

english, 1995

12

Semisynthetic penicillins and cephalosporins containing the substituted 6-vinyl-1,2-dihydro-2-oxo- and 1,4-dihydro-4-oxo-3-pyridinecarboxylic acid side chains. Synthesis and structure-activity relationships.

DEJOHN, DANA, DOMAGALA, JOHN M., HASKELL, THEODORE H., HEIFETZ, CARL L., HUANG, GIN-GUEI, KALTENBRONN, JAMES S., KROLLS, ULDIS

Journal:

The Journal of Antibiotics

Year:

1985

Language:

english

File:

PDF, 5.29 MB

english, 1985

13

ChemInform Abstract: 4- AND 5-ARYL-1-NAPHTHALENEACETIC ACIDS AS ANTIINFLAMMATORY AGENTS

KALTENBRONN, J. S.

Journal:

Chemischer Informationsdienst

Year:

1973

File:

PDF, 208 KB

1973

14

Synthesis of a Bromine-Rich Marine Antibiotic

Hanessian, Stephen, Kaltenbronn, James S.

Journal:

Journal of the American Chemical Society

Year:

1966

Language:

english

File:

PDF, 241 KB

english, 1966

15

Regulator of G Protein Signaling 2 Deficiency Causes Endothelial Dysfunction and Impaired Endothelium-derived Hyperpolarizing Factor-mediated Relaxation by Dysregulating Gi/o Signaling

Osei-Owusu, P., Sabharwal, R., Kaltenbronn, K. M., Rhee, M.-H., Chapleau, M. W., Dietrich, H. H., Blumer, K. J.

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 3.01 MB

english, 2012

16

Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit Gα13

Scherer, Stephanie L, Cain, Matthew D, Kanai, Stanley M., Kaltenbronn, Kevin M, Blumer, Kendall J

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 8.30 MB

english, 2017

17

Prospective analysis of the effect of physician experience with the FAST examination in reducing the use of CT scans

O John Ma, Gary Gaddis, Mark T Steele, David Cowan, Kary Kaltenbronn

Journal:

Emergency Medicine Australasia

Year:

2005

Language:

english

File:

PDF, 85 KB

english, 2005

18

4-(and 5-)(2-Thienyl)-1-naphthaleneacetic acids as antiinflammatory agents

Kaltenbronn, James S., Rhee, Tae O.

Journal:

Journal of Medicinal Chemistry

Year:

1974

Language:

english

File:

PDF, 484 KB

english, 1974

19

GIRK channel modulation by assembly with allosterically regulated RGS proteins

Zhou, H., Chisari, M., Raehal, K. M., Kaltenbronn, K. M., Bohn, L. M., Mennerick, S. J., Blumer, K. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2012

Language:

english

File:

PDF, 863 KB

english, 2012

20

Genetic ablation of calcium-independent phospholipase A2 causes hypercontractility and markedly attenuates endothelium-dependent relaxation to acetylcholine

Dietrich, H. H., Abendschein, D. R., Moon, S. H., Nayeb-Hashemi, N., Mancuso, D. J., Jenkins, C. M., Kaltenbronn, K. M., Blumer, K. J., Turk, J., Gross, R. W.

Journal:

AJP Heart and Circulatory Physiology

Year:

2010

Language:

english

File:

PDF, 2.10 MB

english, 2010

21

ChemInform Abstract: ANTIINFLAMMATORY ACTIVITY OF ISOMERIC PHENYLNAPHTHALENEACETIC ACIDS

KALTENBRONN, J. S.

Journal:

Chemischer Informationsdienst

Year:

1977

File:

PDF, 138 KB

1977

22

Targeting nucleotide exchange to inhibit constitutively active G protein α subunits in cancer cells

Onken, Michael D., Makepeace, Carol M., Kaltenbronn, Kevin M., Kanai, Stanley M., Todd, Tyson D., Wang, Shiqi, Broekelmann, Thomas J., Rao, Prabakar Kumar, Cooper, John A., Blumer, Kendall J.

Journal:

Science Signaling

Year:

2018

Language:

english

File:

PDF, 1.13 MB

english, 2018

23

Structure-activity relationships of the potent combined endothelinA/endothelinB receptor antagonist Ac-DDip16-Leu-Asp-Ile-Ile-Trp21 (PD 142893): development of endothelinB receptor selective antagonists

Cody, Wayne L., He, John X., DePue, Patricia L., Waite, Lisa A., Leonard, Daniele M., Sefler, Andrea M., Kaltenbronn, James S., Haleen, Stephen J., Walker, Donnelle M., Flynn, Michael A., Welch, Kathl

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.56 MB

english, 1995

24

ChemInform Abstract: FUNCTIONALIZATION OF SUBSTITUTED 2(1H)- AND 4(1H)-PYRIDONES. III. THE PREPARATION OF SUBSTITUTED 6-VINYL-1,2-DIHYDRO-2-OXO- AND 1,4-DIHYDRO-4-OXO-3-PYRIDINECARBOXYLIC ACIDS THROUGH THE CHEMISTRY OF PYRIDONE DIANIONS

DEJOHN, D., DOMAGALA, J. M., KALTENBRONN, J. S., KROLLS, U.

Journal:

Chemischer Informationsdienst

Year:

1984

File:

PDF, 227 KB

1984

25

Functionalization of substituted 2(1H)- and 4(1H)-pyridones. III. The preparation of substituted 6-Vinyl-1,2-dihydro-2-oxo- and 1,4-dihydro-4-oxo-3-pyridinecarboxylic acids through the chemistry of pyridone dianions

Dana Dejohn, John M. Domagala, James S. Kaltenbronn, Uldis Krolls

Journal:

Journal of Heterocyclic Chemistry

Year:

1983

File:

PDF, 586 KB

1983

26

C-Terminal Modifications of Histidyl- N -benzylglycinamides To Give Improved Inhibition of Ras Farnesyltransferase, Cellular Activity, and Anticancer Activity in Mice

McNamara, Dennis J., Dobrusin, Ellen, Leonard, Daniele M., Shuler, Kevon R., Kaltenbronn, James S., Quin, John, Bur, Scott, Thomas, Charles E., Doherty, Annette M., Scholten, Jeffrey D., Zimmerman, Ka

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 98 KB

english, 1997

27

ChemInform Abstract: 4-(AND 5-)(2-THIENYL)-1-NAPHTHALENEACETIC ACIDS AS ANTIINFLAMMATORY AGENTS

KALTENBRONN, J. S., RHEE, T. O.

Journal:

Chemischer Informationsdienst

Year:

1974

File:

PDF, 140 KB

1974

28

5-Aryl-2-furanacetic acids

Kaltenbronn, James S., Rhee, Tae O.

Journal:

Journal of Medicinal Chemistry

Year:

1968

File:

PDF, 101 KB

1968

29

Breast Cancer Cell Targeting by Prenylation Inhibitors Elucidated in Living Animals with a Bioluminescence Reporter

Chinault, S. L., Prior, J. L., Kaltenbronn, K. M., Penly, A., Weilbaecher, K. N., Piwnica-Worms, D., Blumer, K. J.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 1.11 MB

english, 2012

30

CI-867, a new broad-spectrum semisynthetic penicillin.

KALTENBRONN, JAMES S., HASKELL, THEODORE H., DOUB, LEONARD, KNOBLE, JAMES, DEJOHN, DANA, KROLLS, ULDIS, JENESEL, NICKOLAS, HUANG, GIN-GUEI, HEIFETZ, CARL L., FISHER, M. W.

Journal:

The Journal of Antibiotics

Year:

1979

Language:

english

File:

PDF, 1.93 MB

english, 1979

31

SYNTHESIS OF [ S -( R ∗, R ∗)] – ETHYL α–[(1–CARBOXYETHYL) AMINO]–BENEZENEBUTANOATE, AN IMPORTANT INTERMEDIATE IN THE SYNTHESIS OF ANGIOTENSIN CONVERTING ENZYME INHIBITORS

Kaltenbronn, James S., Dejohn, Dana, Krolls, Uldis

Journal:

Organic Preparations and Procedures International

Year:

1983

Language:

english

File:

PDF, 237 KB

english, 1983

32

Antiinflammatory activity of isomeric phenylnaphthaleneacetic acids

Kaltenbronn, James S.

Journal:

Journal of Medicinal Chemistry

Year:

1977

Language:

english

File:

PDF, 385 KB

english, 1977

33

ChemInform Abstract: Synthesis and Structure-Activity Relationships of Potent New Angiotensin Converting Enzyme Inhibitors Containing Saturated Bicyclic Amino Acids.

BLANKLEY, C. J., KALTENBRONN, J. S., DEJOHN, D. E., WERNER, A., BENNETT, L. R., BOBOWSKI, G., KROLLS, U., JOHNSON, D. R., PEARLMAN, W. M., HOEFLE, M. L., ESSENBURG, A. D., COHEN, D. M., KAPLAN, H. R.

Journal:

Year:

1987

File:

PDF, 211 KB

1987

34

ChemInform Abstract: STRUCTURE-ACTIVITY RELATIONSHIPS IN A SERIES OF ANTIINFLAMMATORY N-ARYLANTHRANILIC ACIDS

KALTENBRONN, J. S., SCHERRER, R. A., SHORT, F. W., JONES, E. M., BEATTY, H. R., SAKA, M. M., WINDER, C. V., WAX, J., WILLIAMSON, W. R. N.

Journal:

Chemischer Informationsdienst

Year:

1983

File:

PDF, 119 KB

1983

35

Analyses of ligand binding in five endothiapepsin crystal complexes and their use in the design and evaluation of novel renin inhibitors

Lunney, Elizabeth A., Hamilton, Harriet W., Hodges, John C., Kaltenbronn, James S., Repine, Joseph T., Badasso, Mohammed, Cooper, Jon B., Dealwis, Chris, Wallace, Bonnie A.

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 4.56 MB

english, 1993

36

Design and synthesis of potent, selective, and orally active fluorine-containing renin inhibitors

Doherty, Annette M., Sircar, Ila, Kornberg, Brian E., Quin, John, Winters, R. Thomas, Kaltenbronn, James S., Taylor, Michael D., Batley, Brian L., Rapundalo, Stephen R.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 1.60 MB

english, 1992

37

4- and 5-Aryl-1-naphthaleneacetic acids as antiinflammatory agents

Kaltenbronn, James S.

Journal:

Journal of Medicinal Chemistry

Year:

1973

Language:

english

File:

PDF, 515 KB

english, 1973

38

New inhibitors of human renin that contain novel replacements at the P2 site

Doherty, Annette M., Kaltenbronn, James S., Hudspeth, James P., Repine, Joseph T., Roark, William H., Sircar, Ila, Tinney, Frank J., Connolly, Cleo J., Hodges, John C.

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 3.30 MB

english, 1991

39

Anti-writhing activity of some peptides related to neurotensin and tuftsin

E.D. NICOLAIDES, E.A. LUNNEY, J.S. KALTENBRONN, J.N. WILEY, D.A. DOWNS

Journal:

Chemical Biology & Drug Design

Year:

1985

Language:

english

File:

PDF, 404 KB

english, 1985

40

Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure

Tang, Mary, Wang, Guang, Lu, Ping, Karas, Richard H, Aronovitz, Mark, Heximer, Scott P, Kaltenbronn, Kevin M, Blumer, Kendall J, Siderovski, David P, Zhu, Yan

Journal:

Nature Medicine

Year:

2003

Language:

english

File:

PDF, 350 KB

english, 2003

41

Renin inhibitors containing .alpha.-heteroatom amino acids as P2 residues

Repine, Joseph T., Kaltenbronn, James S., Doherty, Annette M., Hamby, James M., Himmelsbach, Richard J., Kornberg, Brian E., Taylor, Michael D., Lunney, ELizabeth A., Humblet, Christine

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 2.05 MB

english, 1992

42

ChemInform Abstract: SYNTHESIS OF (S-(R,R))-ETHYL α-((1-CARBOXYETHYL)AMINO)BENEZENEBUTANOATE, AN IMPORTANT INTERMEDIATE IN THE SYNTHESIS OF ANGIOTENSIN CONVERTING ENZYME INHIBITORS

KALTENBRONN, J. S., DEJOHN, D., KROLLS, U.

Journal:

Chemischer Informationsdienst

Year:

1983

File:

PDF, 145 KB

1983

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